Definition of early age at onset in bipolar disorder according to distinctive neurodevelopmental pathways: insights from the FACE-BD study.
Fiche publication
Date publication
février 2023
Journal
Psychological medicine
Auteurs
Membres identifiés du Cancéropôle Est :
Pr HAFFEN Emmanuel
Tous les auteurs :
Corponi F, Lefrere A, Leboyer M, Bellivier F, Godin O, Loftus J, Courtet P, Dubertret C, Haffen E, Llorca PM, Roux P, Polosan M, Schwan R, Samalin L, Olié E, Etain B, , Seriès P, Belzeaux R
Lien Pubmed
Résumé
Converging evidence suggests that a subgroup of bipolar disorder (BD) with an early age at onset (AAO) may develop from aberrant neurodevelopment. However, the definition of early AAO remains unprecise. We thus tested which age cut-off for early AAO best corresponds to distinguishable neurodevelopmental pathways.
Mots clés
Age at onset, bipolar disorder, machine learning, neurodevelopment
Référence
Psychol Med. 2023 02 28;:1-9