Increased gut permeability and intestinal inflammation precede arthritis onset in the adjuvant-induced model of arthritis.
Fiche publication
Date publication
juin 2023
Journal
Arthritis research & therapy
Auteurs
Membres identifiés du Cancéropôle Est :
Dr PAIS DE BARROS Jean-Paul, Pr HOCQUET Didier
Tous les auteurs :
Hecquet S, Totoson P, Martin H, Algros MP, Saas P, Pais-de-Barros JP, Atchon A, Valot B, Hocquet D, Tournier M, Prati C, Wendling D, Demougeot C, Verhoeven F
Lien Pubmed
Résumé
Intestinal inflammation, dysbiosis, intestinal permeability (IP), and bacterial translocation (BT) have been identified in patients with spondyloarthritis but the time at which they appear and their contribution to the pathogenesis of the disease is still a matter of debate.
Mots clés
Animal models, Dysbiosis, Intestinal inflammation, Intestinal permeability, Microbiota
Référence
Arthritis Res Ther. 2023 06 6;25(1):95