Neurotrophic tropomyosin receptor kinase (NTRK) fusion positive tumors: a historical cohort analysis.

Fiche publication


Date publication

juillet 2023

Journal

Expert review of anticancer therapy

Auteurs

Membres identifiés du Cancéropôle Est :
Dr JANNIER Sarah


Tous les auteurs :
Lemelle L, Guillemot D, Hermann AL, Gauthier A, Carton M, Corradini N, Rome A, Berlanga P, Jourdain A, Marie Cardine A, Jannier S, Boutroux H, Defachelles AS, Aerts I, Geoerger B, Karanian M, Doz F, Brisse HJ, Schleiermacher G, Delattre O, Pierron G, Orbach D

Résumé

NTRK gene fusions have been identified in various tumors; some requiring aggressive therapy and sometimes new TRK inhibitors (TRKi). We aimed to describe a national, unselected, retrospective, multicenter cohort.

Mots clés

Burden of therapy, Fusion transcript tumor, Infantile fibrosarcoma, Neurotrophic tropomyosin receptor kinase, TRK inhibitor

Référence

Expert Rev Anticancer Ther. 2023 07 11;: