Pneumococcal pneumonia and endotoxemia: An experimental and clinical reappraisal.
Fiche publication
Date publication
août 2023
Journal
European journal of clinical investigation
Auteurs
Membres identifiés du Cancéropôle Est :
Pr BINQUET Christine, Dr PAIS DE BARROS Jean-Paul, Pr MASSON David
Tous les auteurs :
Godon J, Charles PE, Nguyen S, de Barros JP, Choubley H, Jacquier M, Tetu J, Quenot JP, Luu M, Binquet C, Masson D, Piroth L, Blot M,
Lien Pubmed
Résumé
Circulating endotoxins could result from bacterial digestive translocation during sepsis, thus contributing to uncontrolled systemic inflammation, leading in turn to organ dysfunction. We addressed this issue in the setting of severe pneumococcal pneumonia.
Mots clés
Streptococcus pneumoniae , endotoxemia, immune response, lipopolysaccharide, pneumonia
Référence
Eur J Clin Invest. 2023 08 29;:e14077