Questions about Using the Induced Membrane Technique to Manage Cases of Congenital Tibial Pseudarthrosis.

Fiche publication


Date publication

juillet 2023

Journal

Cells

Auteurs

Membres identifiés du Cancéropôle Est :
Dr GINDRAUX Florelle


Tous les auteurs :
Klein C, Gindraux F, Masquelet AC, Mentaverri R, Gouron R

Résumé

The induced membrane technique is an innovative approach for repairing critical bone defects and has been applied recently in patients with congenital pseudarthrosis of the tibia (CPT). CPT is frequently associated with neurofibromatosis type 1 (NF1). Here, we briefly describe the clinical results of the induced membrane technique in NF1-deficient patients with CPT and in an animal model of CPT. Furthermore, we discuss the hypotheses used to explain inconsistent outcomes for the induced membrane technique in CPT-especially when associated with NF1.

Mots clés

Masquelet’s technique, children, congenital pseudarthrosis of the tibia, induced membrane, leg, neurofibromatosis 1

Référence

Cells. 2023 07 24;12(14):