Asymmetric Dipyrrin and F-BODIPYs Conjugated to Terminal Alkynes and Alkenes.
Fiche publication
Date publication
juillet 2017
Journal
The Journal of organic chemistry
Auteurs
Membres identifiés du Cancéropôle Est :
Dr FIGLIOLA Carlotta
Tous les auteurs :
Figliola C, Robertson KN, Greening S, Thompson A
Lien Pubmed
Résumé
An asymmetric meso-H dipyrrin featuring a conjugated terminal alkyne substituent was converted to its corresponding difluoro boron complex, and the extent of π-conjugation was extended using Sonogashira cross-coupling. Treatment of the alkyne-substituted dipyrrin with BF·OEt and NEt revealed the reactivity of the conjugated terminal alkyne toward Lewis-activated electrophilic substitution and led to the isolation of F-BODIPYs bearing terminal bromovinyl and enol substituents.
Référence
J Org Chem. 2017 07 7;82(13):7059-7064