Asymmetric Dipyrrin and F-BODIPYs Conjugated to Terminal Alkynes and Alkenes.

Fiche publication


Date publication

juillet 2017

Journal

The Journal of organic chemistry

Auteurs

Membres identifiés du Cancéropôle Est :
Dr FIGLIOLA Carlotta


Tous les auteurs :
Figliola C, Robertson KN, Greening S, Thompson A

Résumé

An asymmetric meso-H dipyrrin featuring a conjugated terminal alkyne substituent was converted to its corresponding difluoro boron complex, and the extent of π-conjugation was extended using Sonogashira cross-coupling. Treatment of the alkyne-substituted dipyrrin with BF·OEt and NEt revealed the reactivity of the conjugated terminal alkyne toward Lewis-activated electrophilic substitution and led to the isolation of F-BODIPYs bearing terminal bromovinyl and enol substituents.

Référence

J Org Chem. 2017 07 7;82(13):7059-7064