Renal Fibrosis and Oxidative Stress Induced by Silica Nanoparticles in Male Rats and Its Molecular Mechanisms.

Fiche publication


Date publication

mars 2024

Journal

Iranian journal of pharmaceutical research : IJPR

Auteurs

Membres identifiés du Cancéropôle Est :
Pr SOULIMANI Rachid


Tous les auteurs :
Aouey B, Boukholda K, Ciobica A, Burlui V, Soulimani R, Chigr F, Fetoui H

Résumé

The utilization of amorphous silica nanoparticles (SiNPs) is gaining popularity in various applications, but it poses a potential risk to human and environmental health. However, the underlying causes and mechanisms of SiNPs-induced kidney damage are still largely unknown.

Mots clés

Matrix Metalloproteinase, Oxidative Stress, Renal Fibrosis, Silica Nanoparticle, TGF-β1

Référence

Iran J Pharm Res. 2024 03 26;23(1):e143703