[Post-traumatic mucormycosis due to Lichtheimia corymbifera: three case reports].
Fiche publication
Date publication
décembre 2014
Journal
Journal de mycologie medicale
Auteurs
Membres identifiés du Cancéropôle Est :
Pr VILLENA Isabelle
Tous les auteurs :
Lambert D, Nerot C, Huguenin A, Diallo S, Mzabi A, Ohl X, Noel V, Rouger C, Strady C, Villena I, Bani-Sadr F, Toubas D
Lien Pubmed
Résumé
We report 3 cases of post-traumatic cutaneous mucormycosis caused by Lichtheimia corymbifera, two of them occurring after a farm working accident. Management of post-traumatic mucormycoses consists of a wide excision of the infected tissue, combined with immediate antifungal therapy. Liposomal amphotericin B is the recommended first line treatment. Few studies have evaluated the efficacy of posaconazole. All 3 patients received a surgical debridement and liposomal amphotericin B, which was followed by posaconazole in 2 cases. The duration of the antifungal treatment is not yet well defined. All three patients received a treatment of five weeks with a favorable outcome.
Mots clés
Cutaneous mucormycosis, Lichtheimia corymbifera, Mucormycoses, Mucormycoses cutanées, Mucormycoses post-traumatiques, Mucormycosis, Posaconazole, Post-traumatic mucormycosis
Référence
J Mycol Med. 2014 Dec;24(4):345-50