CD206 macrophages are relevant non-invasive imaging biomarkers and therapeutic targets in experimental lung fibrosis.

Fiche publication


Date publication

juillet 2024

Journal

Thorax

Auteurs

Membres identifiés du Cancéropôle Est :
Dr GARRIDO Carmen, Dr GONCALVES Victor, Dr COLLIN Bertrand, Dr BELLAYE Pierre-Simon, Pr BONNIAUD Philippe, Mr PERNET Nicolas, Dr BELTRAMO Guillaume, Dr DIAS Alexandre


Tous les auteurs :
Pommerolle L, Beltramo G, Biziorek L, Truchi M, Dias AMM, Dondaine L, Tanguy J, Pernet N, Goncalves V, Bouchard A, Monterrat M, Savary G, Pottier N, Ask K, Kolb MRJ, Mari B, Garrido C, Collin B, Bonniaud P, Burgy O, Goirand F, Bellaye PS

Résumé

Interstitial lung diseases (ILDs) include a large number of diseases associated with progressive pulmonary fibrosis (PPF), including idiopathic pulmonary fibrosis (IPF). Despite the rarity of each of the fibrotic ILDs individually, they cumulatively affect a considerable number of patients. PPF is characterised by an excessive collagen deposition leading to functional decline.

Mots clés

Idiopathic pulmonary fibrosis, Imaging/CT MRI etc, Interstitial Fibrosis, Macrophage Biology

Référence

Thorax. 2024 07 20;: