Investigating the prognostic impact of NY-ESO-1 expression and HLA subtypes in metastatic synovial sarcoma.

Fiche publication


Date publication

août 2024

Journal

ESMO open

Auteurs

Membres identifiés du Cancéropôle Est :
Dr LEROUX Agnès


Tous les auteurs :
Dufresne A, Pokras S, Meurgey A, Chabaud S, Toulmonde M, Bompas E, Le Cesne A, Robin YM, Duffaud F, Valentin T, El Zein S, Leroux A, Dubray-Longeras P, Firmin N, de Pinieux G, Noal S, Delfour C, Bollard J, Tonon L, Biette A, Gadot N, Attignon V, Jean-Denis M, Woessner M, Klohe E, Thayaparan T, Eleftheriadou I, Blouch K, Nathenson MJ, Blay JY

Résumé

To better understand the importance of New York esophageal squamous cell carcinoma 1 (NY-ESO-1) and human leukocyte antigen (HLA) subtype in treatment decision making, further investigation of their prevalence and prognostic impact among patients with metastatic synovial sarcoma (mSS) is needed.

Mots clés

HLA subtypes, NY-ESO-1 expression, adoptive T-cell therapy, metastatic synovial sarcoma

Référence

ESMO Open. 2024 08 16;9(8):103645