Definitive radio(chemo)therapy versus upfront surgery in the treatment of HPV-related localized or locally advanced oropharyngeal squamous cell carcinoma.
Fiche publication
Date publication
juillet 2024
Journal
PloS one
Auteurs
Membres identifiés du Cancéropôle Est :
Dr BERTAUT Aurélie, Dr LADOIRE Sylvain, Pr TRUC Gilles, Dr VULQUIN Noémie, Dr BOUSTANI Jihane
Tous les auteurs :
Baude J, Guigou C, Thibouw D, Vulquin N, Folia M, Constantin G, Boustani J, Duvillard C, Ladoire S, Truc G, Bertaut A, Chevalier C
Lien Pubmed
Résumé
The treatment of stage I-III HPV+ oropharyngeal squamous cell carcinoma (HPV-OPSCC) is based on either surgery ± adjuvant therapy or exclusive radio±chemotherapy. We sought to compare these two therapeutic strategies in terms of efficacy, tolerance and quality of life (QoL).
Mots clés
Humans, Male, Female, Middle Aged, Oropharyngeal Neoplasms, therapy, Quality of Life, Aged, Retrospective Studies, Chemoradiotherapy, methods, Papillomavirus Infections, complications, Squamous Cell Carcinoma of Head and Neck, therapy, Adult, Neoplasm Staging
Référence
PLoS One. 2024 07 25;19(7):e0307658