Total plasma protein in very preterm babies: prognostic value and comparison with illness severity scores.
Fiche publication
Date publication
janvier 2013
Auteurs
Membres identifiés du Cancéropôle Est :
Pr BINQUET Christine, Pr QUANTIN Catherine
Tous les auteurs :
Iacobelli S, Bonsante F, Quantin C, Robillard PY, Binquet C, Gouyon JB
Lien Pubmed
Résumé
OBJECTIVE: We aimed to investigate the predictive value for severe adverse outcome of plasma protein measurements on day one of life in very preterm infants and to compare total plasma protein levels with the validated illness severity scores CRIB, CRIB-II, SNAP-II and SNAPPE-II, regarding their predictive ability for severe adverse outcome. METHODS: We analyzed a cohort of infants born at 24-31 weeks gestation, admitted to the tertiary intensive care unit of a university hospital over 10.5 years. The outcome measure was "severe adverse outcome" defined as death before discharge or severe neurological injury on cranial ultrasound. The adjusted odd ratio (aOR) and 95% confidence interval (95% CI) of severe adverse outcome for hypoproteinemia (total plasma protein level
Référence
PLoS One. 2013 Apr 16;8(4):e62210