[Acquired ichthyosis and livedoid palmoplantar keratoderma: two unusual skin manifestations of systemic lupus erythematosus].

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Date publication

mars 2012

Auteurs

Membres identifiés du Cancéropôle Est :
Pr AUBIN François, Pr HUMBERT Philippe


Tous les auteurs :
Biver-Dalle C, Gil H, Meaux-Ruault N, Mermet-Ginet I, Aubin F, Humbert P, Magy-Bertrand N

Résumé

Acquired ichthyosis and livedoid palmoplantar keratoderma have rarely been described in systemic lupus erythematosus (SLE). In the first case, a 51-year-old man presented with generalized acquired ichthyosis associated with renal glomurelosclerosis and neurolupus. rituximab allowed total resolution of the acquired ichthyosis. A livedoid palmoplantar keratoderma was observed in a 45-year-old woman as the initial clinical manifestation of a systemic lupus erythematosus associated with Raynaud's phenomenon, photosensitivity and inflammatory polyarthralgia. Although the pathophysiology is not well-defined, these unusual cutaneous manifestations should be considered by physicians when diagnosis of SLE is suspected.

Référence

Rev Med Interne. 2012 Mar;33(3):e14-6