Mirror symmetry breaking and chiral amplification in foldamer-based supramolecular helical aggregates.
Fiche publication
Date publication
février 2012
Auteurs
Membres identifiés du Cancéropôle Est :
Pr LEHN Jean-Marie
Tous les auteurs :
Azeroual S, Surprenant J, Lazzara TD, Kocun M, Tao Y, Cuccia LA, Lehn JM
Lien Pubmed
Résumé
Spontaneous asymmetric generation of supramolecular chiral fibers was observed in the folding induced self-assembly of a lock-washer shaped foldamer. A secondary nucleation growth mechanism is proposed to explain the observed chiral amplification or deracemization of these supramolecular fibers.
Référence
Chem Commun (Camb). 2012 Feb 25;48(17):2292-4