PDZ-peptide complexes: as exciting as ever.
Fiche publication
Date publication
octobre 2011
Lien Pubmed
Résumé
In this issue, Babault et al. present a structural analysis of the PDZ domain of the PTPN4 phosphatase, free and bound to target peptides. This allows them to enhance the cell-killing properties of a pro-apoptotic peptide dramatically.
Référence
Structure. 2011 Oct 12;19(10):1350-1.