Silica-based nanoparticles for photodynamic therapy applications.

Fiche publication


Date publication

juillet 2010

Auteurs

Membres identifiés du Cancéropôle Est :
Dr FROCHOT Céline


Tous les auteurs :
Couleaud P, Morosini V, Frochot C, Richeter S, Raehm L, Durand JO

Résumé

Silica-based nanoparticles for applications in photodynamic therapy (PDT) have emerged as a promising field for the treatment of cancer. In this review, based on the pathway the photosensitizer is entrapped inside the silica matrix, the different methods for the synthesis of silica-based nanoparticles are described from the pioneering works to the latest achievements which concern multifunctional nanoplatforms, up-converting nanoparticles, two-photon PDT, vectorization and in vivo applications.

Référence

Nanoscale. 2010 Jul 7;2(7):1083-95