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Pr DEVARENNE-CHARPENTIER Emmanuelle

Fiche personne

coordonnées

UMR CNRS 7369 MEDyC
Campus Moulin de la Housse
BP 1039
51687 REIMS CEDEX 2

03 26 82 39 70

Emmanuelle.charpentier@univ-reims.fr

Territoire

Champagne-Ardenne

Statut

Enseignant-Chercheur

affiliation

Université de Reims Champagne-Ardenne (URCA)

UMR CNRS 7369 MEDyC - Matrice Extracellulaire et Dynamique Cellulaire MEDyC (MEDyC)

équipes/plateformes

Equipe UMR 7369 MEDyC - Equipe "Matrice extracellulaire, Cancer et Cibles thérapeutiques"

Recherche

Expertises :
- Recherche:Biologie Cellulaire
- Recherche:Biologie Moléculaire
- Recherche:Biochimie

Projets

Evaluation in vitro et in vivo du potentiel anti-leucémique de l'éthoxyfagaronine

2012 - Porteur du projet : Pr DEVARENNE-CHARPENTIER Emmanuelle

Evaluation in vitro et in vivo du potentiel anti-leucémique de l'ethoxyfagaronine

2011 - Porteur du projet : Pr DEVARENNE-CHARPENTIER Emmanuelle

Anomalies de l'activation des caspases dans la leucémie myélo-monocytaire chronique et les syndromes myélodysplasiques et rôle de Cdx2 dans leur transformation blastique (ACM-07)

2007 - Porteur du projet : Pr SOLARY Eric - Partenaires : Pr BONNIN Alain, Dr FREUND Jean-Noël, Pr DEVARENNE-CHARPENTIER Emmanuelle, Dr VAN DORSSELAER Alain

Publications

Anti-tumoral effect of Thymelaea hirsuta L. extracts in colorectal cancer cells.

Toumi I, Yatouji S, Borie N, Remy S, Renault JH, Chazee L, Hammami M, Martiny L, Devarenne-Charpentier E, Btaouri HE

Anticancer Agents Med Chem. 2022 08 26;:

Thrombospondin-1 Receptor CD47 Overexpression Contributes to P-Glycoprotein-Mediated Multidrug Resistance Against Doxorubicin in Thyroid Carcinoma FTC-133 Cells.

Courageot MP, Duca L, Martiny L, Devarenne-Charpentier E, Morjani H, El Btaouri H

Front Oncol. 2020 ;10:551228

Intrinsic dynamics study identifies two amino acids of TIMP-1 critical for its LRP-1-mediated endocytosis in neurons.

Verzeaux L, Belloy N, Thevenard-Devy J, Devy J, Ferracci G, Martiny L, Dedieu S, Dauchez M, Emonard H, Etique N, Devarenne-Charpentier E

Sci Rep. 2017 Jul;7(1):5375

Targeting focal adhesion assembly by ethoxyfagaronine prevents lymphoblastic cell adhesion to fibronectin.

Ouchani F, Devy J, Rusciani A, Helesbeux JJ, Salesse S, Letinois I, Gras-Billart D, Duca L, Duval O, Martiny L, Charpentier E

Anal Cell Pathol (Amst). 2012;35(4):267-84

The anti-invasive activity of synthetic alkaloid ethoxyfagaronine on L1210 leukemia cells is mediated by down-regulation of plasminogen activators and MT1-MMP expression and activity.

Devy J, Ouchani F, Oudot C, Helesbeux JJ, Vanquelef E, Salesse S, Rabenoelina F, Al-Khara S, Letinois I, Duval O, Martiny L, Charpentier E

Invest New Drugs. 2011 Oct;29(5):730-41

Role of JNK/ATF-2 pathway in inhibition of thrombospondin-1 (TSP-1) expression and apoptosis mediated by doxorubicin and camptothecin in FTC-133 cells.

El Btaouri H, Morjani H, Greffe Y, Charpentier E, Martiny L

Biochim Biophys Acta. 2011 May;1813(5):695-703

TIMP-1 binding to proMMP-9/CD44 complex localized at the cell surface promotes erythroid cell survival.

Lambert E, Bridoux L, Devy J, Dasse E, Sowa ML, Duca L, Hornebeck W, Martiny L, Petitfrere-Charpentier E

Int J Biochem Cell Biol. 2009 May;41(5):1102-15

Tissue inhibitor of metalloproteinase-1 promotes hematopoietic differentiation via caspase-3 upstream the MEKK1/MEK6/p38alpha pathway.

Dasse E, Bridoux L, Baranek T, Lambert E, Salesse S, Sowa ML, Martiny L, Trentesaux C, Petitfrere E

Leukemia. 2007 Apr;21(4):595-603

Involvement of the Src kinase Lyn in phospholipase C-gamma 2 phosphorylation and phosphatidylinositol 3-kinase activation in Epo signalling.

Boudot C, Dasse E, Lambert E, Kadri Z, Mayeux P, Chretien S, Haye B, Billat C, Petitfrere E

Biochem Biophys Res Commun. 2003 Jan 10;300(2):437-42.

Phosphatidylinositol 3-kinase regulates glycosylphosphatidylinositol hydrolysis through PLC-gamma(2) activation in erythropoietin-stimulated cells.

Boudot C, Kadri Z, Petitfrere E, Lambert E, Chretien S, Mayeux P, Haye B, Billat C

Cell Signal. 2002 Oct;14(10):869-78.