EN DE

Dr VINCOURT Jean-Baptiste

Fiche personne

coordonnées

Biopôle du Campus Santé Brabois
9 Avenue de la Forêt de Haye
BP20199
54505 VANDOEUVRE-LES-NANCY Cedex

03 72 74 66 82

Jean-Baptiste.Vincourt@univ-lorraine.fr

Territoire

Lorraine

Statut

Ingénieur/Technicien

Recherche

Mots clés : protéomique,spectrométrie de masse,identification,quantification,modifications post-traductionnelles

Expertises :
- Plateforme:Protéomique

Projets

Régulation du remodelage matriciel par l'interaction entre la Lysyl OXidase et les propeptides carboxy-terminaux des procollagènes : Vers le mécanisme central du rôle pro-cancéreux et pro-métastatisque de la LOX

2015 - Porteur du projet : Dr VINCOURT Jean-Baptiste

Publications

Deciphering Natural Killer Cell Cytotoxicity Against Medulloblastoma in vitro and in vivo: Implications for Immunotherapy.

Gauthier M, Pierson J, Moulin D, Mouginot M, Bourguignon V, Rhalloussi W, Vincourt JB, Dumas D, Bensoussan D, Chastagner P, Boura C, Decot V

Immunotargets Ther. 2024 06 26;13:319-333

Tissue-specific collagen hydroxylation at GEP/GDP triplets mediated by P4HA2.

Wilhelm D, Wurtz A, Abouelfarah H, Sanchez G, Bui C, Vincourt JB

Matrix Biol. 2023 03 30;:

Characterization of an Innovative Biomaterial Derived From Human Wharton's Jelly as a New Promising Coating for Tissue Engineering Applications.

Fayon A, Helle D, Francius G, Vincourt JB, Regnault V, Dumas D, Menu P, El Omar R

Front Bioeng Biotechnol. 2022 06 13;10:884069

A versatile strategy to synthesize N-methyl-anthranilic acid-labelled glycoprobes for fluorescence-based screening assays.

Bertin-Jung I, Robert A, Ramalanjaona N, Gulberti S, Bui C, Vincourt JB, Ouzzine M, Jacquinet JC, Lopin-Bon C, Fournel-Gigleux S

Chem. Commun. (Camb.). 2020 Aug 13;:

ATDC5 cells as a model of cartilage extracellular matrix neosynthesis, maturation and assembly.

Wilhelm D, Kempf H, Bianchi A, Vincourt JB

J Proteomics. 2020 Feb 22;219:103718

Label-free relative quantification of secreted proteins as a non-invasive method for the quality control of chondrogenesis in bioengineered substitutes for cartilage repair.

Henrionnet C, Gillet P, Mainard D, Vincourt JB, Pinzano A

J Tissue Eng Regen Med. 2017 May;:

Effect of nicotine on the proliferation and chondrogenic differentiation of the human Wharton's jelly mesenchymal stem cells.

Yang X, Qi Y, Avercenc-Leger L, Vincourt JB, Hupont S, Huselstein C, Wang H, Chen L, Magdalou J

Biomed Mater Eng. 2017 ;28(s1):S217-S228

Albumin as a carrier for NO delivery: preparation, physicochemical characterization, and interaction with gold nanoparticles.

Luo M, Boudier A, Pallotta A, Maincent P, Vincourt JB, Leroy P

Drug Dev Ind Pharm. 2016 Dec;42(12):1928-1937

In malignant cartilagenous tumors, immunohistochemical expression of procollagen PC1CP peptide is higher and that of PC2CP lower than in benign cartilaginous lesions.

Delaunay-Lemarie C, Vincourt JB, Marie B, Battaglia-Hsu SF, Etienne S, Sirveaux F, Nguyen Thi PL, Magdalou J, Vignaud JM, Gauchotte G

Virchows Arch. 2015 Sep;467(3):329-37

Label-free relative quantification applied to LC-MALDI acquisition for rapid analysis of chondrocyte secretion modulation.

Riffault M, Moulin D, Grossin L, Mainard D, Magdalou J, Vincourt JB

J Proteomics. 2015 Jan 30;114:263-73

Chondrocalcin is internalized by chondrocytes and triggers cartilage destruction via an interleukin-1beta-dependent pathway.

Bantsimba-Malanda C, Cottet J, Netter P, Dumas D, Mainard D, Magdalou J, Vincourt JB

Matrix Biol. 2013 Oct-Nov;32(7-8):443-51

The cucurbitacins E, D and I: investigation of their cytotoxicity toward human chondrosarcoma SW 1353 cell line and their biotransformation in man liver.

Abbas S, Vincourt JB, Habib L, Netter P, Greige-Gerges H, Magdalou J

Toxicol Lett. 2013 Feb 4;216(2-3):189-99

Measurement of matrilin-3 levels in human serum and synovial fluid using a competitive enzyme-linked immunosorbent assay.

Vincourt JB, Gillet P, Rat AC, Guillemin F, Netter P, Mainard D, Magdalou J

Osteoarthritis Cartilage. 2012 Jul;20(7):783-6

Matrilin-3 switches from anti- to pro-anabolic upon integration to the extracellular matrix.

Vincourt JB, Etienne S, Grossin L, Cottet J, Bantsimba-Malanda C, Netter P, Mainard D, Libante V, Gillet P, Magdalou J

Matrix Biol. 2012 Jun;31(5):290-8

C-propeptides of procollagens I{alpha}1 and II that differentially accumulate in enchondromas versus chondrosarcomas regulate tumor cell survival and migration.

Vincourt JB, Etienne S, Cottet J, Delaunay C, Malanda B, Lionneton F, Sirveaux F, Netter P, Plenat F, Mainard D, Vignaud JM, Magdalou J

Cancer Res. 2010 Jun 1;70(11):4739-48

Increased expression of matrilin-3 not only in osteoarthritic articular cartilage but also in cartilage-forming tumors, and down-regulation of SOX9 via epidermal growth factor domain 1-dependent signaling.

Vincourt JB, Vignaud JM, Lionneton F, Sirveaux F, Kawaki H, Marchal S, Lomazzi S, Plenat F, Guillemin F, Netter P, Takigawa M, Mainard D, Magdalou J

Arthritis Rheum. 2008 Sep;58(9):2798-808.

Establishment of a reliable method for direct proteome characterization of human articular cartilage.

Vincourt JB, Lionneton F, Kratassiouk G, Guillemin F, Netter P, Mainard D, Magdalou J

Mol. Cell Proteomics. 2006 Oct;5(10):1984-95