Mathieu C, Ghosh S, Draussin J, Gasser A, Jacquot G, Banerjee M, Gupta T, Schmutz M, Mirjolet C, Tillement O, Lux F, Klymchenko A, Donzeau M, Pivot X, Harlepp S, Detappe A

Adv Healthc Mater. 2024 03 5;:e2304250

Subcutaneous Administration of a Zwitterionic Chitosan-Based Hydrogel for Controlled Spatiotemporal Release of Monoclonal Antibodies.

Gréa T, Jacquot G, Durand A, Mathieu C, Gasser A, Zhu C, Banerjee M, Hucteau E, Mallard J, Lopez Navarro P, Popescu BV, Thomas E, Kryza D, Sidi-Boumedine J, Ferrauto G, Gianolio E, Fleith G, Combet J, Brun S, Erb S, Cianferani S, Charbonnière LJ, Fellmann L, Mirjolet C, David L, Tillement O, Lux F, Harlepp S, Pivot X, Detappe A

Adv Mater. 2023 12 17;:e2308738

Effect of the Size and Shape of Dendronized Iron Oxide Nanoparticles Bearing a Targeting Ligand on MRI, Magnetic Hyperthermia, and Photothermia Properties-From Suspension to In Vitro Studies.

Freis B, Ramirez MLA, Kiefer C, Harlepp S, Iacovita C, Henoumont C, Affolter-Zbaraszczuk C, Meyer F, Mertz D, Boos A, Tasso M, Furgiuele S, Journe F, Saussez S, Bégin-Colin S, Laurent S

Pharmaceutics. 2023 03 30;15(4):

3D single cell migration driven by temporal correlation between oscillating force dipoles.

Godeau AL, Leoni M, Comelles J, Guyomar T, Lieb M, Delanoë-Ayari H, Ott A, Harlepp S, Sens P, Riveline D

Elife. 2022 07 28;11:

Core-shell iron oxide@stellate mesoporous silica for combined nearinfrared photothermia and drug delivery: influence of pH and surface chemistry

Adam A, Harlepp S, Ghilini F, Cotin G, Freis B, Goetz J, Begin-Colin S, Tasso M, Mertz D

Colloids Surf. A: Physicochem. Eng. Asp.. 2022 ;640:128407

Probing Intravascular Adhesion and Extravasation of Tumor Cells with Microfluidics.

Osmani N, Follain G, Gensbittel V, García-León MJ, Harlepp S, Goetz JG

Methods Mol Biol. 2021 ;2294:111-132

Mechanical Adaptability of Tumor Cells in Metastasis.

Gensbittel V, Kräter M, Harlepp S, Busnelli I, Guck J, Goetz JG

Dev Cell. 2020 Nov 3;:

[Influence of fluid mechanics on metastasis formation].

Follain G, Gensbittel V, Mary B, Lefebvre O, Harlepp S, Hyenne V, Goetz JG

Med Sci (Paris). 2020 Oct;36(10):872-878

Nanocomposite Polymer Scaffolds Responding under External Stimuli for Drug Delivery and Tissue Engineering Applications

Mertz D, Harlepp S, Goetz JG, Bégin D, Schlatter G, Bégin‐Colin S, Hébraud A

. 2020 ;3(2):1900143

Near Infra-Red Light Responsive Carbon Nanotubes@Mesoporous Silica for Photothermia and Drug Delivery to Cancer Cells

Li B, Harlepp S, Gensbittel V, Wells CJR, Bringel O, Goetz JG, Begin-Colin S, Tasso M, Begin D, Mertz D

. 2020 ;17:100308

Fluids and their mechanics in tumour transit: shaping metastasis.

Follain G, Herrmann D, Harlepp S, Hyenne V, Osmani N, Warren SC, Timpson P, Goetz JG

Nat. Rev. Cancer. 2019 Nov 28;:

Metastatic Tumor Cells Exploit Their Adhesion Repertoire to Counteract Shear Forces during Intravascular Arrest.

Osmani N, Follain G, García León MJ, Lefebvre O, Busnelli I, Larnicol A, Harlepp S, Goetz JG

Cell Rep. 2019 Sep 3;28(10):2491-2500.e5

-Heterocyclic Carbene-Platinum Complexes Featuring an Anthracenyl Moiety: Anti-Cancer Activity and DNA Interaction.

Harlepp S, Chardon E, Bouché M, Dahm G, Maaloum M, Bellemin-Laponnaz S

Int J Mol Sci. 2019 Aug 27;20(17):

Studying the Fate of Tumor Extracellular Vesicles at High Spatiotemporal Resolution Using the Zebrafish Embryo.

Hyenne V, Ghoroghi S, Collot M, Bons J, Follain G, Harlepp S, Mary B, Bauer J, Mercier L, Busnelli I, Lefebvre O, Fekonja N, Garcia-Leon MJ, Machado P, Delalande F, López AA, Silva SG, Verweij FJ, van Niel G, Djouad F, Peinado H, Carapito C, Klymchenko AS, Goetz JG

Dev. Cell. 2019 Feb 4;:

Wrapped stellate silica nanocomposites as biocompatible luminescent nanoplatforms assessed in vivo.

Perton F, Harlepp S, Follain G, Parkhomenko K, Goetz JG, Bégin-Colin S, Mertz D

J Colloid Interface Sci. 2019 Jan 23;542:469-482

Hemodynamic Forces Tune the Arrest, Adhesion, and Extravasation of Circulating Tumor Cells.

Follain G, Osmani N, Azevedo AS, Allio G, Mercier L, Karreman MA, Solecki G, Garcia Leòn MJ, Lefebvre O, Fekonja N, Hille C, Chabannes V, Dollé G, Metivet T, Hovsepian F, Prudhomme C, Pichot A, Paul N, Carapito R, Bahram S, Ruthensteiner B, Kemmling A, Siemonsen S, Schneider T, Fiehler J, Glatzel M, Winkler F, Schwab Y, Pantel K, Harlepp S, Goetz JG

Dev. Cell. 2018 Apr 9;45(1):33-52.e12

Design of Protein-Coated Carbon Nanotubes Loaded with Hydrophobic Drugs through Sacrificial Templating of Mesoporous Silica Shells.

Fiegel V, Harlepp S, Begin-Colin S, Begin D, Mertz D

Chemistry. 2018 Mar 26;24(18):4662-4670

Dr HARLEPP Sébastien

Fiche personne

coordonnées

Territoire

Statut

affiliation

équipes/plateformes

Projets

Etude in vivo de nanoplateformes à hyperthermie et délivrance de médicaments activée par champ magnétique radiofréquence et lumière infra-rouge (VivIRMag)

Disséquer la cascade métastatique à l'échelle nanométrique par une approche de microscopie intravitale corrélative (MetaCLEM)

Publications

Defects or no defects? Or how to design 20-25 nm spherical iron oxide nanoparticles to harness both magnetic hyperthermia and photothermia.

Landscape of Subcutaneous Administration Strategies for Monoclonal Antibodies in Oncology.

Supramolecular Heterodimer Peptides Assembly for Nanoparticles Functionalization.