Immobilization of engineered proteins on a nickel chelating molecular wire
Fiche publication
Date publication
janvier 2007
Auteurs
Membres identifiés du Cancéropôle Est :
Pr HAIECH Jacques, Dr SCHULTZ Patrick
Tous les auteurs :
Balavoine F, Girard-Nguyen A, Schultz P, Haiech J, Mioskowski C
Lien Pubmed
Résumé
Biomolecular nanowires were obtained by assembling proteins onto a linear and conducting polymer: a high molecular weight poly(p-phenyleneethynylene) functionalized with nickel(II) N-nitrilotriacetate complexes was found to immobilize histidine-tagged proteins through a specific interaction between nickel complexes and the engineered tags.
Référence
Arkivoc. 2007;:268-77