Site-specific somatic mutagenesis in the retinal pigment epithelium.
Fiche publication
Date publication
mai 2002
Journal
Investigative ophthalmology & visual science
Auteurs
Membres identifiés du Cancéropôle Est :
Pr CHAMBON Pierre, Dr METZGER Daniel
Tous les auteurs :
Mori M, Metzger D, Garnier JM, Chambon P, Mark M
Lien Pubmed
Résumé
Generate site-specific somatic mutations selectively in the retinal pigment epithelium (RPE) in mice.
Mots clés
Animals, DNA, metabolism, Embryo, Mammalian, Female, Hybrid Cells, In Situ Hybridization, Integrases, genetics, Male, Membrane Glycoproteins, Mice, Mice, Transgenic, Mutagenesis, Site-Directed, Oxidoreductases, Pigment Epithelium of Eye, enzymology, Polymerase Chain Reaction, Proteins, genetics, Receptors, Retinoic Acid, genetics, Recombinant Fusion Proteins, genetics, Retinoid X Receptors, Transcription Factors, genetics, Viral Proteins, genetics
Référence
Invest. Ophthalmol. Vis. Sci.. 2002 May;43(5):1384-8