Photochemical aryl radical cyclizations to give (E)-3-ylideneoxindoles.
Fiche publication
Date publication
janvier 2014
Auteurs
Membres identifiés du Cancéropôle Est :
Pr SAPI Janos, Dr GERARD Stéphane
Tous les auteurs :
Gurry M, Allart-Simon I, McArdle P, Gerard S, Sapi J, Aldabbagh F
Lien Pubmed
Résumé
(E)-3-Ylideneoxindoles are prepared in methanol in reasonable to good yields, as adducts of photochemical 5-exo-trig of aryl radicals, in contrast to previously reported analogous radical cyclizations initiated by tris(trimethylsilyl)silane and azo-initiators that gave reduced oxindole adducts.
Référence
Molecules. 2014 Sep 30;19(10):15891-9