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Dr GERARD Stéphane

Fiche personne

coordonnées

Institut de Chimie Moléculaire de Reims
UMR CNRS 7312
51 rue Cognacq Jay
51096 REIMS Cedex

03 26 91 87 07

stephane.gerard@univ-reims.fr

Territoire

Champagne-Ardenne

Statut

Enseignant-Chercheur

affiliation

Université de Reims Champagne-Ardenne (URCA)

Institut de Chimie Moléculaire de Reims - UMR 7312 CNRS (ICMR)

équipes/plateformes

Equipe UMR 7312 - Equipe "Biomolécules : Synthèse et Mécanismes d'Action (BSMA)"

Publications

Synthesis, Hydrolytic Stability and In Vivo Biological Study of Bioconjugates of the Tetrapeptides FELL Containing Pyrrole Moiety.

Borisova B, Vladimirova S, Nocheva H, Laronze-Cochard M, Gérard S, Petrin S, Danalev D

Biomedicines. 2023 12 9;11(12):

Synthesis, In Silico Log Study, and In Vitro Analgesic Activity of Analogs of Tetrapeptide FELL.

Borisova B, Nocheva H, Gérard S, Laronze-Cochard M, Dobrev S, Angelova S, Petrin S, Danalev D

Pharmaceuticals (Basel). 2023 08 21;16(8):

Inhibition of Recruitment and Activation of Neutrophils by Pyridazinone-Scaffold-Based Compounds.

Moniot A, Braux J, Siboni R, Guillaume C, Audonnet S, Allart-Simon I, Sapi J, Tirouvanziam R, Gérard S, Gangloff SC, Velard F

Int J Mol Sci. 2022 06 29;23(13):

Pyridazinone Derivatives Limit Osteosarcoma-Cells Growth In Vitro and In Vivo.

Moniot A, Braux J, Bour C, Guillaume C, Lamret F, Allart-Simon I, Audonnet S, Renault S, Rédini F, Laronze-Cochard M, Sapi J, Gangloff SC, Gérard S, Velard F

Cancers (Basel). 2021 Nov 28;13(23):

Synergy between Indoloquinolines and Ciprofloxacin: An Antibiofilm Strategy against .

Charpentier E, Doudet L, Allart-Simon I, Colin M, Gangloff SC, Gérard S, Reffuveille F

Antibiotics (Basel). 2021 Oct 4;10(10):

Pyridazinone derivatives as potential anti-inflammatory agents: synthesis and biological evaluation as PDE4 inhibitors.

Allart-Simon I, Moniot A, Bisi N, Ponce-Vargas M, Audonnet S, Laronze-Cochard M, Sapi J, Hénon E, Velard F, Gérard S

RSC Med Chem. 2021 Apr 28;12(4):584-592

Mechanistic insights into Smiles rearrangement. Focus on π-π stacking interactions along the radical cascade.

Khartabil H, Doudet L, Allart-Simon I, Ponce-Vargas M, Gérard S, Hénon E

Org. Biomol. Chem.. 2020 Aug 26;:

Synthesis and biological evaluation of pyridazinone derivatives as potential anti-inflammatory agents.

Barberot C, Moniot A, Allart-Simon I, Malleret L, Yegorova T, Laronze-Cochard M, Bentaher A, Médebielle M, Bouillon JP, Hénon E, Sapi J, Velard F, Gérard S

Eur J Med Chem. 2018 Feb 25;146:139-146

Radical Smiles Rearrangement: An Update.

Allart-Simon I, Gérard S, Sapi J

Molecules. 2016 Jul;21(7):

Diastereomer Interconversion via Enolization: A Case Study.

Renzetti A, Di Crescenzo A, Nie F, Bond AD, Gérard S, Sapi J, Fontana A, Villani C

Chirality. 2015 Nov;27(11):779-83

TiCl-promoted condensation of methyl acetoacetate, isobutyraldehyde, and indole: a theoretical and experimental study.

Renzetti A, Marrone A, Gerard S, Sapi J, Nakazawa H, Re N, Fontana A

Phys Chem Chem Phys. 2015 Mar 9.

Photochemical aryl radical cyclizations to give (E)-3-ylideneoxindoles.

Gurry M, Allart-Simon I, McArdle P, Gerard S, Sapi J, Aldabbagh F

Molecules. 2014 Sep 30;19(10):15891-9

Cyclopropyl-tryptamine analogues: synthesis and biological evaluation as 5-HT(6) receptor ligands.

Szalata C, Szymoniak J, Fabis F, Butt-Gueulle S, Rault S, Bertus P, Gerard S, Sapi J

ChemMedChem. 2013 Jan;8(1):70-3

First domino radical cyclisation/Smiles rearrangement combination.

Pudlo M, Allart-Simon I, Tinant B, Gerard S, Sapi J

Chem Commun (Camb). 2012 Feb 28;48(18):2442-4

Multicomponent reactions studies: Yonemitsu-type trimolecular condensations promoted by Ti(IV) derivatives

Gerard S, Renzetti A, Lefevre B, Fontana A, de Maria P, Sapi J

Tetrahedron. 2010 Apr 17;66(16):3065-9

Diastereoselective trimolecular condensation between indole, Meldrum's acid and chiral sugar-derived aldehydes

Dardennes E, Gerard S, Petermann C, Sapi J

Tetrahedron-asymmetry. 2010 Feb 22;21(2):208-15

Condensation of beta-diester titanium enolates with carbonyl substrates: a combined DFT and experimental investigation.

Marrone A, Renzetti A, De Maria P, Gerard S, Sapi J, Fontana A, Re N

Chemistry. 2009 Nov 2;15(43):11537-50.

TiCl4/Et3N-promoted three-component condensation between aromatic heterocycles, aldehydes, and active methylene compounds.

Renzetti A, Dardennes E, Fontana A, De Maria P, Sapi J, Gerard S

J Org Chem. 2008 Sep 5;73(17):6824-7

Synthesis of new cyclopropanated tryptamine analogues

Szalata C, Sapi J, Szymoniak J, Bertus P, Gerard S

Synlett. 2008 Jun 13;10:1479-82

A new approach to the synthesis of N-alkylated 2-substituted azetidin-3-ones.

Gerard S, Raoul M, Sapi J

Eur J Org Chem. 2006 May 12;10:2440-5.

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