The long-lasting shadow of litter size in rodents: litter size is an underreported variable that strongly determines adult physiology.
Fiche publication
Date publication
mars 2023
Journal
Molecular metabolism
Auteurs
Membres identifiés du Cancéropôle Est :
Pr VERGELY Catherine
Tous les auteurs :
Parra-Vargas M, Bouret SG, Bruning JC, de Moura EG, Garland T, Lisboa PC, Ozanne SE, Patti ME, Plagemann A, Speakman JR, Tena-Sempere M, Vergely C, Zeltser LM, Jiménez-Chillarón JC
Lien Pubmed
Résumé
Litter size is a biological variable that strongly influences adult physiology in rodents. Despite evidence from previous decades and recent studies highlighting its major impact on metabolism, information about litter size is currently underreported in the scientific literature. Here, we urge that this important biological variable should be explicitly stated in research articles.
Mots clés
Childhood obesity, Experimental models of physiology, Litter size reduction, Neonatal growth
Référence
Mol Metab. 2023 03 16;71:101707