EN DE

Dr MUKHERJI Atish

Fiche personne

coordonnées

Institut de Recherche sur les Maladies Virales et Hépatiques
3 rue Koeberlé
67000 STRASBOURG

03 68 85 36 99

mukherji@unistra.fr

Territoire

Alsace

Statut

Chercheur

affiliation

Inserm UMR_S 1110 - Institut de Recherche sur les Maladies Virales et Hépatiques (Inserm UMR_S1110)

équipes/plateformes

Equipe UMR_S 1110 - Equipe "Analyse moléculaire et translationelle des interactions virus-hôte et maladies hépatiques"

Recherche

Publications

An atlas of the human liver diurnal transcriptome and its perturbation by hepatitis C virus infection.

Mukherji A, Jühling F, Simanjuntak Y, Crouchet E, Del Zompo F, Teraoka Y, Haller A, Baltzinger P, Paritala S, Rasha F, Fujiwara N, Gadenne C, Slovic N, Oudot MA, Durand SC, Ponsolles C, Schuster C, Zhuang X, Holmes J, Yeh ML, Abe-Chayama H, Heikenwälder M, Sangiovanni A, Iavarone M, Colombo M, Foung SKH, McKeating JA, Davidson I, Yu ML, Chung RT, Hoshida Y, Chayama K, Lupberger J, Baumert TF

Nat Commun. 2024 08 29;15(1):7486

Targeting the liver clock improves fibrosis by restoring TGF-β signaling.

Crouchet E, Dachraoui M, Jühling F, Roehlen N, Oudot MA, Durand SC, Ponsolles C, Gadenne C, Meiss-Heydmann L, Moehlin J, Martin R, Brignon N, Del Zompo F, Teraoka Y, Aikata H, Abe-Chayama H, Chayama K, Saviano A, Heide D, Onea M, Geyer L, Wolf T, Felli E, Pessaux P, Heikenwälder M, Chambon P, Schuster C, Lupberger J, Mukherji A, Baumert TF

J Hepatol. 2024 08 20;:

Cell-based cccDNA reporter assay combined with functional genomics identifies YBX1 as HBV cccDNA host factor and antiviral candidate target.

Verrier ER, Ligat G, Heydmann L, Doernbrack K, Miller J, Maglott-Roth A, Jühling F, El Saghire H, Heuschkel MJ, Fujiwara N, Hsieh SY, Hoshida Y, Root DE, Felli E, Pessaux P, Mukherji A, Mailly L, Schuster C, Brino L, Nassal M, Baumert TF

Gut. 2022 12 9;:

Perturbation of the circadian clock and pathogenesis of NAFLD.

Mukherji A, Dachraoui M, Baumert TF

Metab. Clin. Exp.. 2020 Aug 11;:154337

Targeting clinical epigenetic reprogramming for chemoprevention of metabolic and viral hepatocellular carcinoma.

Jühling F, Hamdane N, Crouchet E, Li S, El Saghire H, Mukherji A, Fujiwara N, Oudot MA, Thumann C, Saviano A, Roca Suarez AA, Goto K, Masia R, Sojoodi M, Arora G, Aikata H, Ono A, Tabrizian P, Schwartz M, Polyak SJ, Davidson I, Schmidl C, Bock C, Schuster C, Chayama K, Pessaux P, Tanabe KK, Hoshida Y, Zeisel MB, Duong FH, Fuchs BC, Baumert TF

Gut. 2020 Mar 26;:

Combined Analysis of Metabolomes, Proteomes, and Transcriptomes of HCV-infected Cells and Liver to Identify Pathways Associated With Disease Development.

Lupberger J, Croonenborghs T, Roca Suarez AA, Van Renne N, Jühling F, Oudot MA, Virzì A, Bandiera S, Jamey C, Meszaros G, Brumaru D, Mukherji A, Durand SC, Heydmann L, Verrier ER, El Saghire H, Hamdane N, Bartenschlager R, Fereshetian S, Ramberger E, Sinha R, Nabian M, Everaert C, Jovanovic M, Mertins P, Carr SA, Chayama K, Dali-Youcef N, Ricci R, Bardeesy NM, Fujiwara N, Gevaert O, Zeisel MB, Hoshida Y, Pochet N, Baumert TF

Gastroenterology. 2019 Apr 9;:

The Circadian Clock and Liver Function in Health and Disease.

Mukherji A, Bailey SM, Staels B, Baumert TF

J. Hepatol.. 2019 Mar 28;:

Similarities and differences in the transcriptional control of expression of the mouse TSLP gene in skin epidermis and intestinal epithelium.

Ganti KP, Mukherji A, Surjit M, Li M, Chambon P

Proc. Natl. Acad. Sci. U.S.A.. 2017 Feb;114(6):E951-E960

Shifting eating to the circadian rest phase misaligns the peripheral clocks with the master SCN clock and leads to a metabolic syndrome.

Mukherji A, Kobiita A, Damara M, Misra N, Meziane H, Champy MF, Chambon P

Proc. Natl. Acad. Sci. U.S.A.. 2015 Dec;112(48):E6691-8

Shifting the feeding of mice to the rest phase creates metabolic alterations, which, on their own, shift the peripheral circadian clocks by 12 hours.

Mukherji A, Kobiita A, Chambon P

Proc. Natl. Acad. Sci. U.S.A.. 2015 Dec;112(48):E6683-90